- exposure pathway： 口服生物利用度为 50%-60%。
- Toxicity summary： 根据推测的作用机制，氨基 Levulinic acid(ALA)外用溶液施用后产生的光敏化作用是通过 ALA 代谢转化为原卟啉 IX(PpIX)，PpIX 在皮肤中积累。当暴露于适当波长和能量的光线时，积累的 PpIX 产生光动力反应，这是一种依赖于光和氧气同时存在的细胞毒性过程。光的吸收导致卟啉分子处于激发态，随后从 PpIX 到氧分子的自旋转移生成单线态氧，它可以进一步反应形成超氧化物和羟基自由基。使用氨基 Levulinic acid...
- Carcinogen Classification： 对人类无致癌性指示（未列入 IARC）。
- Drug Induced Liver Injury： 参考文献: DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation： . ◉ 对泌乳和母乳的影响
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Research chemical CAS 106-60-5 98% 1g
Research chemical CAS 106-60-5 98% 1g, complete specifications, for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
