Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

Azide-PEG4-VC-PAB-Doxorubicin

英文名称

Azide-PEG4-VC-PAB-Doxorubicin

货号

A767851-1mg

包装规格

1mg

浓度

≥98%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

Azide-PEG4-VC-PAB-Doxorubicin 是由 linker Azide-PEG4-VC-PAB 和毒性分子 Doxorubicin 连接而成的，可用来制备抗体偶联活性分子。Azide-PEG4-VC-PAB-Doxorubicin 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。它还可以和含有 DBCO 或 BCN 基团的分子发生环张力驱动的炔-叠氮环加成反应 (SPAAC)。 Azide-PEG4-VC-PAB-Doxorubicin is composed of the linker Azide-PEG4-VC-PAB and the toxic molecule Doxorubicin, and can be used to prepare antibody conjugated active molecules. Azide-PEG4-VC-PAB-Doxorubicin is a click chemistry reagent. It contains Azide groups and can undergo copper catalyzed azide alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo ring tension driven alkyne azide cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.

生化机理

Azide-PEG4-VC-PAB-Doxorubicin is a agent-linker conjugate composed of a cytotoxic anthracycline antibiotic Doxorubicin and a linker Azide-PEG4-VC-PAB to make antibody agent conjugate (ADC). Azide-PEG4-VC-PAB-Doxorubicin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

分子式

C57H75N9O21

分子量

1222.25 g/mol

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！