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Product introduction
3,6-二氨基吖啶是一种氨基吖啶,是3位和6位被氨基取代的吖啶。它是一种缓慢作用的抑菌剂,对许多革兰氏阳性菌有效(但对孢子无效),其盐类以前用于治疗烧伤和感染伤口。它具有发色团、嵌入剂、抗菌剂、防腐药物和致癌剂的作用。它是3,6-二氨基吖啶(1+)的共轭碱。
Chinese name
吖啶-3,6-二胺, DNA 干扰剂
English name
acridine-3,6-diamine
Chinese alias
3,6-二氨基吖啶 | 3,6-吖啶二胺 | 原黄素
English alias
AE-562/12222295 | Progarmed | CCRIS 1244 | HY-B1741 | YSCH0132 | 3,6-ACRIDINEDIAMINE | A909942 | AI3-52128 | NCI60_004643 | Proflavin hemisulfate;3,6-Diaminoacridine hemisulfate | Q420454 | 1qvt | 2,8-Diaminoacridine (European) | AT13412 | AB00375967_04 |
CAS number
92-62-6
molecular formula
C13H11N3
molecular weight
209.25
Exact mass
-
PSA
64.9
Logp
1.8
Safety
  • Hazard summary: 普洛凡和其盐类用作局部抗菌剂;无可用流行病学研究,动物数据不足以进行评估;[IARC] 已报告过敏性接触性皮炎;腹腔内LD50 (小鼠) = 50 mg/kg;[Sax] 刺激物;[MSDSonline]
  • Human toxicity extract: /SPECIAL STUDIES/ 研究了结构相关的嵌入剂原黄素和9-氨基吖啶在MRC-5人成纤维细胞培养物中诱导非计划DNA合成(UDS)和改变半保留DNA复制的作用……原黄素影响DNA合成,但未引起任何UDS。
  • non-human toxicity value: LD50 小鼠皮下 140 mg/kg
  • Hazard categories and classifications: STOT SE 3 (97.5%)
  • Antidote and first aid: 尿素的产生和使用作为肥料和动物饲料预计会导致其直接释放到环境中。尿素作为化学中间体、炸药稳定剂、药物和粘度调节剂的生产和使用,以及在塑料、粘合剂、药物、化妆品、牙膏、阻燃剂和制备脲的生产和使用,可能导致其通过各种废物流释放到环境中。尿素是氮和蛋白质代谢的天然产物;它存在于尿液和动物废物中。如果释放到空气中,25°C时的蒸气压为1.20×10-5 mm Hg,表明尿素将在大气中同时存在于气相和颗粒相。气相尿素将通过与光化学产生的羟基反应在大气中降解...
  • Evidence for Carcinogenicity: 致癌性分类:1) 人类证据:无数据;2) 动物证据:有限。对人类致癌风险的总体总结评估为第 3 组:该物质对人类的致癌性无法分类。/原黄素盐;摘自表格/
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acridine-3, 6-diamine 10mM in DMSO 1ml

acridine-3, 6-diamine 10mM in DMSO 1ml Macklin 92-62-6, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:A793322-1ml
Product model:1ml
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Lead Time:30days
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