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Product introduction
物理描述 | 醋磺己脲是一种白色蓬松的结晶粉末,几乎没有气味。(NTP, 1992)
Chinese name
乙酰己酰胺, 磺酰脲受体 1、Kir6.2 阻断剂
English name
1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea
Chinese alias
-
English alias
acetohexamide | 968-81-0 | Dymelor | Acetohexamid | Gamadiabet | Dimelor | Hypoglicil | Metaglucina | Tsiklamid | Minoral | Ordimel | Acetohexamida | Acetohexamidum | N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea | 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexyl
CAS number
968-81-0
molecular formula
C15H20N2O4S
molecular weight
324.4
Exact mass
-
PSA
101
Logp
2.4
Safety
  • Health hazard: 急性/慢性危害:加热分解时,该化合物会释放出硫氧化物和氮氧化物等剧毒烟雾。(NTP, 1992)
  • reactive group: 磺酸盐、膦酸盐和硫代膦酸盐,有机
  • Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
  • First aid measures: 食入:不要催吐。如果受害者意识清醒且没有抽搐,给予1-2杯水稀释化学物质,并立即呼叫医院或中毒控制中心。如果医生建议,准备将受害者送往医院。如果受害者抽搐或昏迷,不要经口给予任何东西,确保受害者的气道通畅,让受害者侧卧,头部低于身体。不要催吐。立即将受害者送往医院。(NTP, 1992)
  • fire hazard: 该化学品的闪点数据不可用;但可能是可燃的。(NTP, 1992)
  • fire fighting: 涉及此化学品的火灾可用干粉、二氧化碳或哈龙灭火器扑灭。(NTP, 1992)
  • Primary Hazards: 未分类
  • Special Reports: DHEW/NCI; 乙酰己酰脲致癌性生物测定(1980) 技术报告系列第50号 DHEW出版物编号 (NIH) 78-850
  • reactivity profile: 一种酰胺。有机酰胺/酰亚胺与偶氮和重氮化合物反应生成有毒气体。有机酰胺/酰亚胺与强还原剂反应生成易燃气体。酰胺是非常弱的碱(比水弱)。酰亚胺的碱性更弱,实际上与强碱反应形成盐。也就是说,它们可以作为酸反应。将酰胺与脱水剂如P2O5或SOCl2混合会生成相应的腈。这些化合物的燃烧会产生氮的混合氧化物(NOx)。
  • Human toxicity extract: 昏迷或精神状态改变通常是大多数(90%)摄入过量磺酰脲类药物患者最重要的表现症状.../磺酰脲/
  • Other safety information: 化学品评估:IMAP评估 - 4-乙酰基-N-[(环己基氨基)羰基]苯磺酰胺:环境I级评估
  • Air and water reaction: 不溶于水。
  • Hazard categories and classifications: 未分类
  • Non-human toxic extract: 乙酰己酰脲刺激正常及alloxan糖尿病大鼠肝脏匀浆中的酶。显然药物干扰肝脏蛋白质生物合成和糖异生。口服。
  • Non-fire leakage response: 储存注意事项:您应在室温下储存此材料。(NTP, 1992)
  • Personal protective equipment (PPE): 推荐呼吸器:在称量和稀释纯测试化学品时,佩戴NIOSH批准的半面罩呼吸器,配备有机蒸气/酸性气体 cartridges(专门用于有机蒸气、HCl、酸性气体和SO2)和粉尘/雾过滤器。(NTP,1992)
  • Carcinogen Classification: 总结:在本生物测定条件下,结论是醋己脲对Fischer 344大鼠和B6C3F1小鼠不具有致癌性。
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: ◉ 对哺乳和母乳的影响
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Cu acidJi amide 10mM in DMSO 1ml

Cu acidJi amide 10mM in DMSO 1ml Macklin 968-81-0, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:A794419-1ml
Product model:1ml
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Lead Time:30days
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