Reactant for preparation of: . Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP . Cytotoxic and antimitotic agents . Insulin-like growth factor 1 receptor inhibitors . Antitumoral agents . Factor Xa inhibitor . Potential antivascular agents . Gli1-mediated transcription in the Hedgehog pathway . Inhibitors of receptor tyrosine kinase with antiangiogenic effects . PKCθ inhibitors . HIV protease inhibitors Reactant for preparation of: . Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP . Cytotoxic and antimitotic agents . Insulin-like growth factor 1 receptor inhibitors . Antitumoral agents . Factor Xa inhibitor . Potential antivascular agents . Gli1-mediated transcription in the Hedgehog pathway . Inhibitors of receptor tyrosine kinase with antiangiogenic effects . PKCθ inhibitors . HIV protease inhibitors