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Product introduction
AFN-1252 是一种选择性 FabI 抑制剂,FabI 是葡萄球菌属脂肪酸生物合成的必需酶。AFN-1252 对葡萄球菌表现出高度选择性活性。AFN-1252 对金黄色葡萄球菌的不同临床分离株的 MIC90 值 ⩽0.015 μg/ml。AFN-1252 在败血症小鼠模型中有效,可提供 100% 的保护,防止金黄色葡萄球菌的致命腹膜感染。 AFN-1252 is a selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 exhibits typical MIC90 values of ⩽0.015 μg/ml against diverse clinical isolates of S. aureus. AFN-1252 is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith
Chinese name
AFN-1252
English name
AFN-1252
Chinese alias
-
English alias
Benzenesulfonamide, N-((1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl- | AFN1252 | AFN-1252 | API-1252;Debio 1452 | BDBM50052244 | A901058 | AFN-1252(Debio 1452) | API 1252 | QXTWSUQCXCWEHF-JXMROGBWSA-N | (E)-N-methyl-N-[(3-methyl-1-benzofuran-2-yl)
CAS number
620175-39-5
molecular formula
C22H21N3O3
molecular weight
375.42 g/mol
Exact mass
≥98%
PSA
75.400 Ų
Logp
2.5
Technical Documents
「No technical documents」
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AFN-1252 ≥98% 2mg

AFN-1252 ≥98% 2mg CAS 620175-39-5, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:A878161-2mg
Product model:2mg
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Lead Time:30days
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