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Product introduction
Aminooxy-PEG3-azide 是一种不可降解 (non-cleavable) 的含 3 个单元 PEG 的 ADC linker,可用于合成抗体偶联活性分子 (ADC)。Aminooxy-PEG3-azide 也是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。Aminooxy-PEG3-azide 是一种点击化学试剂。它含有 Azide 基团,可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应(CuAAc)。它还可以和含有 DBCO 或 BCN 基团的分子发生环张力驱动的炔-叠氮环加成反应 (SPAAC)。 Aminooxy-PEG3-azide is a PEG derivative containing an aminooxy group and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage.
Chinese name
氨氧基-PEG3-叠氮化物
English name
Aminooxy-PEG3-azide
Chinese alias
-
English alias
-
CAS number
1306615-51-9
molecular formula
C8H18N4O4
molecular weight
234.25 g/mol
Exact mass
≥95%
PSA
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Aminooxy-PEG3-azide 98% 1mg

Aminooxy-PEG3-azide 98% 1mg CAS 1306615-51-9, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:A937119-1mg
Product model:1mg
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Lead Time:30days
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