NEFM Mouse mAb

抗体

中分子量神经丝蛋白抗体 | 中分子量神经丝蛋白单克隆抗体 | NEFM抗体 | NEFM单克隆抗体 | Neurofilament-M抗体 | Neurofilament-M单克隆抗体 | NF-M抗体 | NF-M单克隆抗体

NEF3 | NEF3neurofilament medium polypeptide | NEFM | Neurofilament 3 | neurofilament, medium polypeptide 150kDa | neurofilament, medium polypeptide | neurofilament-3 (150 kD medium) | NFM | NF-M | NF-M160 kDa neurofilament protein | 150kDa medium antibody

Liquid

Ab086656-10μl

10μl

已验证

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3

0.02% Sodium azide

Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. Post-translational: There are a number of repeats of the tripeptide K-S-P, NFM is phosphorylated on a number of the serines in this motif. It is thought that phosphorylation of NFM results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. Phosphorylation seems to play a major role in the functioning of the larger neurofilament polypeptides (NF-M and NF-H), the levels of phosphorylation being altered developmentally and coincident with a change in the neurofilament function. Phosphorylated in the Head and Rod regions by the PKC kinase PKN1, leading to inhibit polymerization.

Recombinant protein of human NEFM (AA 413-773).

小鼠(Mouse)

人(Human)

NEFM

WB: 293T lysates. IHC: Human skin, adult heart, adult brain, melanoma, embryonic liver, muscle, embryonic brain, embryonic, cerebellum, testicular cancer tissues.

150 kDa

Unconjugated

Mouse IgG1 | Rabbit IgG

单克隆抗体

Protein A/G purified

OTI5B7

Whole IgG