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Product details

名称

24p3R Antibody

分子类型

抗体

别名

24p3R抗体 | 可溶性载质转运蛋白22A17抗体 | 24p3R抗体 | 24p3R多克隆抗体 | 可溶性载质转运蛋白22A17抗体

英文别名

物理外观

Liquid

货号

Ab086670-10μl

包装规格

10μl

级别

无载体

浓度

1.0 mg/mL

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

4℃ 短期储存（1-2 周）。-20℃长期保存（12 个月）。收货后建议分装。避免冷冻/解冻循环。

储存缓冲液

0.42% Potassium phosphate, 0.87% Sodium chloride, 30% Glycerol, 0.01% Sodium azide, pH 7.3.

防腐剂

0.01% Sodium azide

生化机理

Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

免疫原

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SLC22A17.

宿主种属

兔(Rabbit)

种属反应性

人(Human), 大鼠(Rat), 小鼠(Mouse), 牛(Cow) | 人(Human),大鼠(Rat),小鼠(Mouse),牛(Cow)

特异性

24p3R

阳性对照

WB: SK-N-SH, SH-SY5Y and Hep G2 cell lysates.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Rabbit IgG

克隆类型

多克隆抗体

纯化方法

mmunogen affinity purified

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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Research chemical 10μl; 1. 0 mg

Name: Research chemical 10μl; 1. 0 mg
Brand: 阿拉丁
SKU: Ab086670-10μl

Research chemical 10μl; 1. 0 mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10μl; 1. 0 mg.

item number：Ab086670-10μl

Product model：10μl

level： 10μl; 1. 0 mg

Lead Time：30days

sold 115 Items

Ask Solution engineer

Specifications：

10μl

Qty

Research chemical 10μl; 1. 0 mg

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