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Product details
名称
Recombinant ALIX Antibody
分子类型
抗体
别名
Anti-ALIX抗体 | ALIX抗体 | ALIX重组抗体 | 程序性细胞死亡6-相互作用蛋白抗体
英文别名
PDC6I_HUMAN | Programmed cell death 6-interacting protein | AIP1 | ALIX | KIAA1375 | PDCD6-interacting protein | ALG-2-interacting protein 1 | ALG-2-interacting protein X | Hp95 | AIP1 antibody | ALG 2 interacting protein 1 antibody | ALG-2-interacting pr
物理外观
Liquid
货号
Ab088156-100μl
包装规格
100μL
级别
重组
浓度
1.2 mg/mL
储存温度
-20°C储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
4°C 短期储存(1-2 周)。-20°C下长期保存(24个月)。收货后建议分装。避免冷冻/解冻循环。
储存缓冲液
50mM Tris-Glycine, 150mM NaCl, 40% Glycerol, 0.05% BSA, 0.01% Sodium azide, pH 7.4
防腐剂
0.01% Sodium azide
生化机理
Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
免疫原
A synthetic peptide derived from human ALIX (AA 3-102)
宿主种属
兔(Rabbit)
种属反应性
人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)
特异性
PDCD6IP
阳性对照
WB: HeLa, MCF7, Jurkat, A549, K562, NIH/3T3 and C6 cell lysates.
SDS-PAGE
150 kDa
偶联
Unconjugated
亚型
Rabbit IgG
克隆类型
重组抗体
轻链亚型
kappa
纯化方法
Protein A purified
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
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「No technical documents」
Articles
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Research chemical 100μL; 1. 2 mg

Research chemical 100μL; 1. 2 mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 100μL; 1. 2 mg.

item number:Ab088156-100μl
Product model:100μL
level: 100μL; 1. 2 mg
Lead Time:30days
sold 988 Items
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Specifications:

100μL

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