BECN1 Mouse mAb

抗体

BECN1 小鼠单克隆抗体 | BECN1 小鼠单抗 | BECN1抗体 | BECN1单克隆抗体 | Beclin 1抗体 | 苄氯素1抗体 | Beclin 1单克隆抗体

Coiled-coil myosin-like BCL2-interacting protein | Protein GT197 | APG6 antibody | ATG 6 antibody | ATG6 antibody | ATG6 autophagy related 6 homolog antibody | Bcl-2-interacting protein beclin antibody | Beclin 1 (coiled coil moesin like BCL2 interacting

Liquid

Ab090922-100μl

100μL

无载体

1.0mg/mL

-20°C储存,避免反复冻融

超低温冰袋运输

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (36 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

10mM PBS, 0.05% Sodium azide, pH 7.4.

0.05% Sodium azide

Plays a central role in autophagy. Acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abscission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis. May play a role in antiviral host defense. Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors. (Microbial infection) Protects against infection by a neurovirulent strain of Sindbis virus.

Recombinant protein of human BECN1 (AA 51-248).

小鼠(Mouse)

人(Human)

BECN1

WB: Hela, A431, MCF-7, Raji, Jurkat and SKBR-3 cell lysate; IHC: breast cancer tissues and liver cancer tissues; Flow: Raji cells.

150kDa

Unconjugated

Mouse IgG1 | IgG1

单克隆抗体

kappa

Protein G purified

2A4

Whole IgG