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Product details

名称

Recombinant CD44 Antibody

分子类型

抗体

别名

英文别名

物理外观

Liquid

货号

Ab094860-10μl

包装规格

10μl

级别

重组

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。

储存缓冲液

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4.

防腐剂

0.02% Sodium azide

生化机理

细胞表面受体，在细胞-细胞相互作用、细胞粘附和迁移中发挥作用，帮助细胞感知组织微环境的变化并做出反应。从而参与多种细胞功能，包括 T 淋巴细胞的活化、再循环和归巢、造血、炎症和对细菌感染的反应。通过其外结构域与透明质酸/HA、胶原蛋白、生长因子、细胞因子或蛋白酶等细胞外基质成分结合，并通过其胞质结构域组装含有受体激酶和膜蛋白酶的蛋白质复合物，从而成为信号转导的平台。这些效应因子包括 PKN2、RhoGTP 酶 RAC1 和 RHOA、Rho 激酶和磷脂酶 C，它们协调信号通路，促进钙动员和肌动蛋白介导的细胞骨架重组，对细胞迁移和粘附至关重要。

免疫原

A synthetic peptide derived from human CD44 (AA 1-250).

宿主种属

兔(Rabbit)

种属反应性

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

特异性

CD44

阳性对照

WB: HeLa, A549, RAW 264.7 and C6 cell lysates. IP: HeLa lysates.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Rabbit IgG

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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