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Product details

名称

Recombinant CD53 Antibody

分子类型

抗体

别名

CD53抗体 | 四旋蛋白25抗体

英文别名

物理外观

Liquid

货号

Ab095014-10μl

包装规格

10μl

级别

重组

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

4℃ 短期储存（1-2 周）。-20℃长期保存（24 个月）。收货后建议分装。避免冷冻/解冻循环。

储存缓冲液

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4.

防腐剂

0.02% Sodium azide

生化机理

被称为富集四跨蛋白微域（TERMs）的特化膜微域的结构成分，是受体聚集和信号传导的平台。因此参与多种生物功能，如细胞信号传导、粘附、迁移和蛋白质贩运。在激活单核细胞和 B 细胞中发挥作用。通过促进白细胞介素-7 受体/IL7R 信号转导，成为 B 细胞发育的重要调节因子。通过将 PKC 募集到质膜使其底物磷酸化，促进 B 细胞中的 BCR 信号传导。通过稳定 L-选择素/SELL 细胞表面的表达，在 B 细胞和 T 细胞向淋巴结归巢的过程中发挥重要作用。通过促进 TNF-α 和 LPS 信号传导，还可介导肝细胞和脂肪组织的代谢和炎症功能，而不受免疫系统的影响。

免疫原

A synthetic peptide derived from human CD53 (AA 180-219).

宿主种属

兔(Rabbit)

种属反应性

人(Human)

特异性

CD53

阳性对照

WB: Jurkat, Raji and Ramos cell lysates.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Rabbit IgG

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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