Share to
Details
Safety
Related
Technical Documents
Articles
reviews
Consult
returns
Product details
名称
CYP1A1 Mouse mAb
分子类型
抗体
别名
CYP1A1抗体 | 细胞色素P450 1A1抗体
英文别名
AHH antibody | AHRR antibody | Aryl hydrocarbon hydroxylase antibody | CP11 antibody | CP1A1_HUMAN antibody | CYP 1 antibody | CYP1 antibody | cyp1a1 antibody | CYPIA1 antibody | Cytochrome P1 450 dioxin inducible antibody | Cytochrome P1-450 antibody | C
物理外观
Liquid
货号
Ab098550-10μl
包装规格
10μl
级别
无载体
浓度
0.5 mg/mL
储存温度
-20°C储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
4℃ 短期储存(1-2 周)。-20℃长期保存(12 个月)。收货后建议分装。避免冷冻/解冻循环。
储存缓冲液
10mM PBS, 30% Glycerol, 0.01% Sodium azide, pH 7.3.
防腐剂
0.01% Sodium azide
生化机理
一种细胞色素 P450 单加氧酶,参与脂肪酸、类固醇激素和维生素等多种内源性底物的代谢。从机理上讲,它利用分子氧将一个氧原子插入底物,并将第二个氧原子还原成水分子,两个电子由 NADPH 通过细胞色素 P450 还原酶(NADPH--血蛋白还原酶)提供。催化碳-氢键的羟化反应。在从雌酮(E1)和 17beta-雌二醇(E2)生成羟基雌激素(即 2-羟基 E1 和 E2,以及在 C15-α 和 C16-α 位上 D 环羟基化的 E1 和 E2)方面具有很高的催化活性。对多不饱和脂肪酸(PUFA)羟基化具有不同的区域选择性。催化某些多不饱和脂肪酸双键的环氧化作用。将花生四烯酸转化为环二十碳三烯酸(EET)异构体 8,9-、11,12- 和 14,15-EET,这些异构体在血管系统中发挥脂质介质的作用。在二十碳五烯酸(EPA)的环氧化反应中具有绝对的立体选择性,可产生 17(R)、18(S) 对映体。可能在肝外组织的全反式维甲酸生物合成中发挥重要作用。催化全反式视黄醇向全反式视黄醛的两次连续氧化转化,然后转化为活性形式全反式视黄酸。还可能参与二十烷酸代谢,将过氧化氢转化为氧化代谢物(脂氧合酶样反应,不依赖于 NADPH)。
免疫原
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CYP1A1.
宿主种属
小鼠(Mouse)
种属反应性
人(Human), 小鼠(Mouse) | 人(Human),小鼠(Mouse)
特异性
CYP1A1
阳性对照
WB: Mouse lung, Jurkat, Hep G2 and HeLa lysates.
SDS-PAGE
150 kDa
偶联
Unconjugated
亚型
Mouse IgG1
克隆类型
单克隆抗体
纯化方法
Protein G purified
克隆号
V55SV
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
Articles
「No related articles yet」
user reviews
Loading...
Consultation

Warm reminder:

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.!

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ,We will handle it for you as soon as possible, thank you for your support and trust.!

Research chemical 10μl; 0. 5 mg

Research chemical 10μl; 0. 5 mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10μl; 0. 5 mg.

item number:Ab098550-10μl
Product model:10μl
level: 10μl; 0. 5 mg
Lead Time:30days
sold 489 Items
Ask Solution engineer
Specifications:

10μl

Qty

Recommended for you