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Product details

名称

Cytochrome C Mouse mAb

分子类型

抗体

别名

英文别名

物理外观

Liquid

货号

Ab098695-100μl

包装规格

100μL

级别

无载体

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融

储存缓冲液

10mM PBS, 50% Glycerol, 0.05% Proclin 300, pH7.4

防腐剂

0.05% Proclin 300

生化机理

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

免疫原

Recombinant CYCS expressed in E.coli (AA 5-100)

宿主种属

小鼠(Mouse)

种属反应性

人(Human), 原鸡属(Gallus), 大鼠(Rat), 小鼠(Mouse), 山羊(Goat), 狗(Dog), 猪(Pig), 豚鼠(Guinea pig) | 人(Human),原鸡属(Gallus),大鼠(Rat),小鼠(Mouse),山羊(Goat),狗(Dog),猪(Pig),豚鼠(Guinea pig)

特异性

CYCS

阳性对照

WB: HEK293, Jurkat, HeLa, Hep G2, A549 and LNCaP cell lysates. IHC: Human cerebellum, cardiac muscle, small intestine, lymph node tissues. ICC/IF: Hep G2, HeLa cells.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Mouse IgG2a

克隆类型

单克隆抗体

轻链亚型

kappa

纯化方法

Protein A + Protein G purified

克隆号

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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Consultation

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