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Product details
名称
Recombinant DPP4 Antibody
分子类型
抗体
别名
DPP4/CD26重组兔单克隆抗体 | DPP4/CD26单克隆抗体 | DPP4/CD26抗体
英文别名
CD26 antigen antibody | ADA-binding protein antibody | ADABP antibody | ADCP 2 antibody | ADCP-2 antibody | Anti-DPP4 antibody | DPP4 antibody | ADCP2 antibody | Adenosine deaminase complexing protein 2 antibody | CD 26 antibody | CD26 antibody | CD26 ant
物理外观
Liquid
货号
Ab100398-10μl
包装规格
10μl
级别
重组
浓度
见COA
储存温度
-20°C储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
4°C 短期储存(1-2 周)。-20°C下长期保存(24个月)。收货后建议分装。避免冷冻/解冻循环。
储存缓冲液
10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH7.4
防腐剂
0.02% Sodium azide
生化机理
细胞表面糖蛋白受体,参与 T 细胞受体(TCR)介导的 T 细胞活化所必需的成本刺激信号。通过至少与 ADA、CAV1、IGF2R 和 PTPRC 结合,充当 T 细胞共激活的正调控因子。它与 CAV1 和 CARD11 的结合可诱导 T 细胞增殖,并以 T 细胞受体/CD3 依赖性方式激活 NF-kappa-B。它与 ADA 的相互作用还能调节淋巴细胞与上皮细胞的粘附。与 FAP 共同参与细胞外基质(ECM)的细胞周蛋白水解、内皮细胞向 ECM 的迁移和入侵。可能参与促进淋巴内皮细胞的粘附、迁移和管形成。过表达时,可增强细胞增殖,而这一过程会受到 GPC3 的抑制。它也是一种具有二肽活性的丝氨酸外肽酶,通过裂解循环中的多肽(包括许多趋化因子、有丝分裂生长因子、神经肽和肽类激素)来调节各种生理过程。从具有未取代 N 末端的多肽中依次去除 N 末端二肽,前提是倒数第二个残基是脯氨酸。
免疫原
A synthetic peptide derived from human CD26 (AA 721-766)
宿主种属
兔(Rabbit)
种属反应性
人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)
特异性
DPP4
阳性对照
WB: U-87 MG, SH-SY5Y, HaCaT, A-375, C6, MOLT-4, PC-3, LNCaP clone FGC, Saos-2, HCT 116, NCCIT, Ramos, HUVEC, Mouse lung, brain, heart, liver, skin, kidney, Rat brain, kidney, heart, skin lysates.
SDS-PAGE
150 kDa
偶联
Unconjugated
亚型
Rabbit IgG
克隆类型
重组抗体
轻链亚型
kappa
纯化方法
Protein A purified
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
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「No related articles yet」
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Research chemical 10μl

Research chemical 10μl; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10μl.

item number:Ab100398-10μl
Product model:10μl
level: 10μl
Lead Time:30days
sold 343 Items
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10μl

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