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Product details
名称
Recombinant EBI3 Antibody
分子类型
抗体
别名
EBI3抗体
英文别名
IL27B | IL35B | IL-27B | cytokine receptor | EBI3 | EBI-3 | EBV-induced gene 3 protein | Epstein-Barr virus induced 3 | Epstein-Barr virus induced gene 3 | Epstein-Barr virus-induced gene 3 protein | IL-27 beta | IL-27 subunit beta | IL35 EBI3 | IL-35 EBI
物理外观
Liquid
货号
Ab100865-10μl
包装规格
10μl
级别
重组
浓度
见COA
储存温度
-20°C储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
4℃ 短期储存(1-2 周)。-20℃长期保存(24 个月)。收货后建议分装。避免冷冻/解冻循环。
储存缓冲液
10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4
防腐剂
0.02% Sodium azide
生化机理
与 IL27 结合形成 IL-27 白细胞介素,这是一种异源二聚体细胞因子,在先天免疫中发挥作用。IL-27 具有促炎和抗炎特性,可调节 T 辅助细胞的发育、抑制 T 细胞增殖、刺激细胞毒性 T 细胞的活性、诱导 B 细胞的同种型转换,并对先天性免疫细胞产生多种影响。它的靶细胞包括 CD4 T 辅助细胞,这些细胞可分化为 1 型效应细胞(TH1)、2 型效应细胞(TH2)和产生 IL17 的辅助 T 细胞(TH17)。它能促使幼稚 CD4 T 细胞快速克隆扩增,但不能促使记忆 CD4 T 细胞快速克隆扩增。它还与 IL-12 强烈协同,触发幼稚 CD4 T 细胞产生干扰素-γ/IFN-γ,并与细胞因子受体 WSX-1/TCCR 结合。IL-27 的另一个重要作用是其抗肿瘤活性和抗血管生成活性,能激活抗血管生成趋化因子的产生。
免疫原
A synthetic peptide derived from human IL 27B (AA 200-229)
宿主种属
兔(Rabbit)
种属反应性
人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)
特异性
EBI3
阳性对照
WB: Hep G2, MCF7 and C6 cell lysates.
SDS-PAGE
150 kDa
偶联
Unconjugated
亚型
Rabbit IgG
克隆类型
重组抗体
轻链亚型
kappa
纯化方法
Protein A purified
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
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Research chemical 10μl

Research chemical 10μl; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10μl.

item number:Ab100865-10μl
Product model:10μl
level: 10μl
Lead Time:30days
sold 125 Items
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Specifications:

10μl

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