FEN1 Antibody

抗体

结构特异性核酸酶FEN1抗体 | FEN1抗体 | FEN1多克隆抗体

RAD2 | FEN-1 | DNase IV antibody | FEN-1 antibody | FEN1 antibody | FEN1_HUMAN antibody | Flap endonuclease 1 antibody | Flap structure specific endonuclease 1 antibody | MF1 | Flap structure-specific endonuclease 1 antibody | hFEN-1 antibody | hFEN1 anti

Liquid

Ab103172-10μl

10μl

无载体

1.0 mg/mL

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

0.42% Potassium phosphate, 0.87% Sodium chloride, 30% Glycerol, 0.01% Sodium azide, pH 7.3

0.01% Sodium azide

Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.

A synthetic peptide derived from human FEN1

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse), 猴(Monkey) | 人(Human),大鼠(Rat),小鼠(Mouse),猴(Monkey)

FEN1

WB: Jurkat, A375, Raji, NIH/3T3 and C6 cell lysates. IHC: Human breast cancer tissue. ICC/IF: MCF7 cells.

150 kDa

Unconjugated

Rabbit IgG

多克隆抗体

Immunogen affinity purified

Whole IgG