GBP2 Mouse mAb

抗体

GBP2抗体 | GBP2单克隆抗体 | 鸟苷酸结合蛋白2抗体

GBP 2 antibody | GTP binding protein 2 antibody | Guanine nucleotide binding protein 2antibody | Guanylate binding protein 2 interferon inducibleantibody | HuGBP 2 antibody | HuGBP2 antibody | Interferon induced guanylate binding protein 2 antibody | GBP2

Liquid

Ab104951-10μl

10μl

已验证

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

4°C 下运输。在 +4°C 下短期储存（1-2 周）。收货后建议分装。长期储存于 -20°C。避免冷冻/解冻循环。

10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3.

0.02% Sodium azide

Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens. Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP. Following infection, recruited to the pathogen-containing vacuoles or vacuole-escaped bacteria and acts as a positive regulator of inflammasome assembly by promoting the release of inflammasome ligands from bacteria. Acts by promoting lysis of pathogen-containing vacuoles, releasing pathogens into the cytosol. Following pathogen release in the cytosol, promotes recruitment of proteins that mediate bacterial cytolysis: this liberates ligands that are detected by inflammasomes, such as lipopolysaccharide (LPS) that activates the non-canonical CASP4/CASP11 inflammasome or double-stranded DNA (dsDNA) that activates the AIM2 inflammasome. Confers protection to the protozoan pathogen Toxoplasma gondii. Independently of its GTPase activity, acts as an inhibitor of various viruses infectivity, such as HIV-1, Zika and influenza A viruses, by inhibiting FURIN-mediated maturation of viral envelope proteins.

Recombinant full length protein of human GBP2.

小鼠(Mouse)

人(Human)

GBP2

WB: HeLa, A549, MCF7 cell lysates. IHC: Human colon, colon adenocarcinoma, ovary, pancreas, endometrium, prostate, bladder, bladder carcinoma tissues. IF/ICC: COS7 cells transiently transfected with pCMV6-ENTRY GBP2. Flow Cytometry: HEK293T cells transfec

150 kDa

Unconjugated

Mouse IgG1

单克隆抗体

Protein G purified

OTI4E7

Whole IgG