HIF-2-alpha Antibody

抗体

缺氧诱导因子2alpha抗体 | 缺氧诱导因子2alpha多抗 | 缺氧诱导因子2alpha多克隆抗体

Basic helix loop helix PAS protein MOP2 antibody | Basic-helix-loop-helix-PAS protein MOP2 antibody | bHLHe73 antibody | Class E basic helix-loop-helix protein 73 antibody | ECYT4 antibody | Endothelial PAS domain containing protein 1 antibody | Endotheli

Liquid

Ab107509-10μl

10μl

已验证

1.0 mg/mL

-20°C储存,避免反复冻融

超低温冰袋运输

4℃ 短期储存（1-2 周）。-20℃长期保存（12 个月）。收货后建议分装。避免冷冻/解冻循环。

10mM PBS, 50% Glycerol, 0.5% BSA, 0.02% Sodium azide, pH7.2

0.02% Sodium azide

Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.

A synthetic peptide derived from human EPAS-1 around the non-acetylation site of K385.

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

HIF-2-alpha

WB: HEK293, MCF7 and SH-SY5Y cell lysates. IHC: Human mammary cancer and colon tissues. ICC/IF: Human stomach and Mouse spleen tissues.

150 kDa

Unconjugated

Rabbit IgG

多克隆抗体

Immunogen affinity purified

Whole IgG