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Product details

名称

Recombinant Hsp70 Antibody

分子类型

抗体

别名

热休克蛋白70重组抗体

英文别名

物理外观

Liquid

货号

Ab108909-10μl

包装规格

10μl

级别

重组

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

储存缓冲液

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4

防腐剂

0.02% Sodium azide

生化机理

In cooperation with other chaperones, the Hsp70 family stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.Tissue specificity: HSPA1B is testis-specific.

免疫原

A synthetic peptide derived from human Hsp70 (AA 400-641)

宿主种属

兔(Rabbit)

种属反应性

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

特异性

HSPA1A, HSPA1B

阳性对照

WB: Mouse heart, Mouse liver, HeLa, K562, A549, NIH/3T3 and C6 lysates. IHC: Human squamous carcinoma, testis cancer, prostate cancer, breast tissues. IF/ICC: HeLa cells.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Rabbit IgG

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

Format

Whole IgG

表位

Epitope mapping with a panel of Hsp 70 deletion mutants suggests that the epitope recognized is located between amino acids 437-479 of human Hsp 70.

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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