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Product details

名称

IL3RA/CD123 Mouse mAb

分子类型

抗体

别名

IL3RA/CD123抗体 | IL3RA/CD123单克隆抗体 | 白介素3受体α抗体

英文别名

物理外观

Liquid

货号

Ab110306-10μl

包装规格

10μl

级别

已验证

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存4℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

储存缓冲液

10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3.

防腐剂

0.02% Sodium azide

生化机理

Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program.

免疫原

Recombinant full length protein of human IL3RA/CD123 produced in HEK293T cell.

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

IL3RA/CD123

阳性对照

WB: HEK293T transfected with pCMV6-ENTRY IL3RA cDNA for 48 hrs; KG-1a lysates. Flow Cytometry: 293T, KG-1a cells.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Mouse IgG2b

克隆类型

单克隆抗体

纯化方法

Protein A purified

克隆号

OTI10D1

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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