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Product details

名称

Integrin alpha 4/CD49d Rat mAb

分子类型

抗体

别名

CD49d抗体

英文别名

物理外观

Liquid

货号

Ab110789-10μg

包装规格

10μg

级别

无载体

浓度

≥95%(SDS-PAGE&SEC-HPLC)

储存温度

-80℃储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

2 - 8°C短期储存（1 个月）。-80°C下长期保存（12个月）。收货后建议分装。避免冷冻/解冻循环。

储存缓冲液

10mM PBS, 150mM NaCl, pH 7.2-7.4

生化机理

整合素α-4/β-1（VLA-4）和α-4/β-7 是纤维粘连蛋白的受体。它们能识别纤维粘连蛋白的替代剪接 CS-1 和 CS-5 区域中的一个或多个结构域。它们也是 VCAM1 的受体。整合素α-4/β-1 可识别 VCAM1 中的 Q-I-D-S 序列。整合素α-4/β-7 也是 MADCAM1 的受体。它能识别 MADCAM1 中的 L-D-T 序列。在活化的内皮细胞上，整合素 VLA-4 触发大多数 VLA-4 阳性白细胞系的同型聚集。它还可能参与细胞溶解性 T 细胞与靶细胞的相互作用。

免疫原

AKR/Cum mouse Spontaneous T lymphoma line TK1

宿主种属

大鼠(Rat)

种属反应性

小鼠(Mouse)

特异性

Integrin alpha 4/CD49d

阳性对照

Flow Cyt: Human whole peripheral blood cells. IHC-Fr: Human tonsil tissue. ICC/IF: Wild-type HAP-1 cells.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Rat IgG2b

克隆类型

单克隆抗体

轻链亚型

kappa

纯化方法

Protein A/G purified

克隆号

R1-2

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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