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Product details

名称

IRF9 Antibody

分子类型

抗体

别名

英文别名

IFN alpha responsive transcription factor subunit antibody | IFN-alpha-responsive transcription factor subunit antibody | Interferon regulatory factor 9 antibody | interferon stimulated transcription factor 3 antibody | Interferon-stimulated gene factor 3

物理外观

Liquid

货号

Ab111008-10μl

包装规格

10μl

级别

已验证

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存2-8℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

储存缓冲液

10mM PBS, 40% Glycerol, 0.05% Sodium azide, pH 7.4.

防腐剂

0.05% Sodium azide

生化机理

Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

免疫原

Fusion protein of human IRF9.

宿主种属

兔(Rabbit)

种属反应性

人(Human)

特异性

IRF9

阳性对照

WB: MCF-7 lysates. IHC: Human ovarian cancer tissue.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Rabbit IgG

克隆类型

多克隆抗体

纯化方法

Antigen affinity purified

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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