Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

KLHL2 Mouse mAb

分子类型

抗体

别名

KLHL2抗体 | KLHL2单克隆抗体 | Kelch样蛋白2抗体

英文别名

物理外观

Liquid

货号

Ab112273-10μl

包装规格

10μl

级别

已验证

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存4℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

储存缓冲液

10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3.

防腐剂

0.02% Sodium azide

生化机理

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, WNK1, WNK3 and WNK4, leading most often to their proteasomal degradation (PubMed:23838290). The BCR(KLHL2) complex catalyzes ubiquitination and degradation of NPTXR (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4 (PubMed:23838290). Plays a role in the reorganization of the actin cytoskeleton (PubMed:10397770). Promotes growth of cell projections in oligodendrocyte precursors (PubMed:15715669).

免疫原

Recombinant protein of human KLHL2 (AA 1-100 & 494-593) produced in HEK293T cell.

宿主种属

小鼠(Mouse)

种属反应性

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

特异性

KLHL2

阳性对照

WB: HEK293T transfected with pCMV6-ENTRY KLHL2 cDNA for 48 hrs; Jurkat lysates. IF/ICC: COS7 cells transiently transfected with pCMV6-ENTRY KLHL2. Flow Cytometry: HEK293T cells transfected with pCMV6-ENTRY KLHL2.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Mouse IgG2b

克隆类型

单克隆抗体

纯化方法

Protein A purified

克隆号

OTI6D8

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！