Recombinant LC3B Antibody

抗体

LC3B重组抗体 | 自噬微管相关蛋白轻链β3抗体 | 微管关联蛋白1轻链3β抗体 | 重组LC3B抗体

ATG8F antibody | Autophagy-related protein LC3 B antibody | Autophagy-related ubiquitin-like modifier LC3 B antibody | LC3B antibody | LC3II antibody | MAP1 light chain 3 like protein 2 antibody | MAP1 light chain 3-like protein 2 antibody | MAP1A/1BLC3 a

Liquid

Ab112866-100μl

100μL

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

4°C 短期储存（1-2 周）。-20°C下长期保存（24个月）。收货后建议分装。避免冷冻/解冻循环。

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4

0.02% Sodium Azide

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover. Upon nutrient stress, directly recruits cofactor JMY to the phagophore membrane surfaces and promotes JMY's actin nucleation activity and autophagosome biogenesis during autophagy.

A synthetic peptide derived from human LC3B (AA 1-110).

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

LC3B

WB: HeLa, A549, MCF7, Raji, RAW 264.7 and C6 cell lysates.

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG