Recombinant Lipocalin-2/NGAL Antibody

抗体

Anti-Lipocalin-2 / NGAL 抗体 | Lipocalin-2 / NGAL 抗体 | Lipocalin-2 / NGAL 重组抗体

24p3 | 25 kDa alpha-2-microglobulin-related subunit of MMP-9 | HNL | LCN2 | lipocalin 2 (oncogene 24p3) | lipocalin 2 | Lipocalin2 | Lipocalin-2 | migration-stimulating factor inhibitor | MSFI | neutrophil gelatinase-associated lipocalin | NGAL | NGALlipo

Liquid

Ab113227-10μl

10μl

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

4°C 下运输。在 +4°C 下短期储存（1-2 周）。收货后建议分装。长期储存于 -20°C。避免冷冻/解冻循环。

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH7.4

0.02% Sodium azide

Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.

A synthetic peptide derived from human NGAL (AA 50-100)

兔(Rabbit)

人(Human)

LCN2

WB: HT-29 and COLO 205 cell lysates.

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG