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Product details

名称

METTL14 Antibody

分子类型

抗体

别名

METTL14抗体 | METTL14多克隆抗体 | 甲基转移酶样蛋白14抗体 | 甲基转移酶样蛋白14多克隆抗体

英文别名

物理外观

Liquid

货号

Ab115157-100μl

包装规格

100μL

级别

无载体

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

储存缓冲液

10mM PBS, 0.09% Sodium azide, pH 7.4.

防腐剂

0.09% Sodium azide

生化机理

Protein Function: N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability (PubMed:24316715, PubMed:24407421, PubMed:25719671). M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop. M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization.

免疫原

A KLH conjugated synthetic peptide from the human region of human METTL14 (AA 2-36)

宿主种属

兔(Rabbit)

种属反应性

人(Human), 小鼠(Mouse) | 人(Human),小鼠(Mouse)

特异性

METTL14

阳性对照

WB: A431, Jurkat, HeLa and HEK293 cell lysates. IHC: Human testis tissue.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Rabbit IgG

克隆类型

多克隆抗体

纯化方法

Protein A purified + Peptide affinity purified

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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