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Product details

名称

Recombinant Myosin light chain kinase/MLCK Antibody

分子类型

抗体

别名

肌球蛋白轻链激酶(MYLK)单克隆抗体 | Myosin light chain kinase/MLCK抗体 | Anti-Myosin light chain kinase/MLCK抗体

英文别名

物理外观

Liquid

货号

Ab116903-10μl

包装规格

10μl

级别

重组

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

4°C 短期储存（1-2 周）。-20°C下长期保存（24个月）。收货后建议分装。避免冷冻/解冻循环。

储存缓冲液

10mM PBS, 50% Glycerol, 0.05% Proclin 300, pH 7.4

防腐剂

0.02% Sodium azide

生化机理

钙/钙调蛋白依赖性酶，通过肌球蛋白轻链（MLC）的磷酸化参与平滑肌收缩。还通过非激酶活性调节肌动蛋白与肌球蛋白的相互作用（相似）。参与调节内皮和血管的通透性。在神经系统中，它被证明能控制培养物中星形胶质细胞的生长启动过程，并参与培养的交感神经节细胞之间形成的突触的递质释放。是导致成纤维细胞凋亡的信号序列的关键参与者。

免疫原

A synthetic peptide derived from human MLCK (AA 1850-1914)

宿主种属

兔(Rabbit)

种属反应性

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

特异性

MYLK

阳性对照

WB: HUVEC, A431 and HEK293 cell lysates. IHC: Human colon tissue.IF/ICC: HeLa cells.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Rabbit IgG

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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