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Product details

名称

NEIL1 Antibody

分子类型

抗体

别名

核酸内切酶8样蛋白1抗体

英文别名

物理外观

Liquid

货号

Ab117503-10μl

包装规格

10μl

级别

无载体

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存2-8℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

储存缓冲液

10mM PBS, 40% Glycerol, 0.05% Sodium azide, pH 7.4.

防腐剂

0.05% Sodium azide

生化机理

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Has DNA glycosylase/lyase activity towards mismatched uracil and thymine, in particular in U:C and T:C mismatches.

免疫原

Fusion protein of human NEIL1.

宿主种属

兔(Rabbit)

种属反应性

人(Human)

特异性

NEIL1

阳性对照

WB: HeLa, Human cerebrum lysates. IHC: Human colorectal, tonsil cancer tissue.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Rabbit IgG

克隆类型

多克隆抗体

纯化方法

Antigen affinity purified

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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