Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

OSBP1 Mouse mAb

分子类型

抗体

别名

OSBP1抗体 | OSBP1单克隆抗体 | 氧固醇结合蛋白1抗体 | 氧化固醇结合蛋白抗体

英文别名

物理外观

Liquid

货号

Ab119397-10μl

包装规格

10μl

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存4℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

储存缓冲液

10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3.

防腐剂

0.02% Sodium azide

生化机理

Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability.

免疫原

Recombinant full length protein of human OSBP1 produced in HEK293T cell.

宿主种属

小鼠(Mouse)

种属反应性

人(Human), 大鼠(Rat), 小鼠(Mouse), 猴(Monkey) | 人(Human),大鼠(Rat),小鼠(Mouse),猴(Monkey)

特异性

OSBP1

阳性对照

WB: HEK293T transfected with pCMV6-ENTRY OSBP cDNA for 48 hrs; COS7, Jurkat lysates. IHC: breast adenocarcinoma, ovary adenocarcinoma tissues.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Mouse IgG1

克隆类型

单克隆抗体

纯化方法

Protein G purified

克隆号

OTI1A4

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！