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Product details
名称
PAK4 Mouse mAb
分子类型
抗体
别名
p21激活激酶4多克隆抗体 | p21激活激酶4抗体 | PAK4小鼠单克隆抗体 | PAK4小鼠单抗
英文别名
EC 2.7.11.1 | p21-activated kinase 4 | PAK-4 | KIAA1142 antibody | p21 activated kinase 4 antibody | p21 Cdc42/Rac1-actiated kinase 4 antibody | P21 protein (Cdc42/Rac) activated kinase 4 antibody | p21(CDKN1A) activated kinase 4 antibody | p21-activated
物理外观
Liquid
货号
Ab120121-10μl
包装规格
10μl
级别
无载体
浓度
1.0 mg/mL
储存温度
-80℃储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
在 2-8 ℃ 下保存(3 个月)。在 -20 ℃ 下保存(12 个月)。在 -80 ℃ 下保存(36 个月)。收货后建议分装。避免冷冻/解冻循环。
储存缓冲液
150mM PBS, 0.09% Sodium azide, pH 7.4
防腐剂
0.09% Sodium azide
生化机理
激活 JNK 通路。在肌动蛋白细胞骨架的重组和丝状体的形成中发挥作用。使蛋白磷酸酶 SSH1 磷酸化并失活,导致肌动蛋白结合/解聚因子 cofilin 的抑制性磷酸化增加。cofilin 活性的降低可能会导致肌动蛋白丝的稳定。使 ARHGEF2 磷酸化。 翻译后:被 CDC42/p21 激活时,丝氨酸残基上会自动磷酸化。受 FGFR2 刺激时,在酪氨酸残基上磷酸化。
免疫原
Recombinant human PAK4 (AA 101-220).
宿主种属
小鼠(Mouse)
种属反应性
人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)
特异性
PAK4
阳性对照
WB: HEK293, Jurkat, HeLa, MCF7, LNCaP, NIH/3T3 and C6 cell lysates. IHC: Human prostate tissue. IP: HEK293 lysates.
SDS-PAGE
150 kDa
偶联
Unconjugated
亚型
Mouse IgG1
克隆类型
单克隆抗体
轻链亚型
kappa
纯化方法
Protein A purified
克隆号
K1E023_12G11
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
Articles
「No related articles yet」
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Research chemical 10μl; 1. 0 mg

Research chemical 10μl; 1. 0 mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10μl; 1. 0 mg.

item number:Ab120121-10μl
Product model:10μl
level: 10μl; 1. 0 mg
Lead Time:30days
sold 576 Items
Ask Solution engineer
Specifications:

10μl

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