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Product details

名称

PKMYT1 Mouse mAb

分子类型

抗体

别名

髓鞘转录因子1激酶抗体 | 髓鞘转录因子1激酶单克隆抗体 | PKMYT1抗体 | PKMYT1单克隆抗体

英文别名

物理外观

Liquid

货号

Ab122151-10μl

包装规格

10μl

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存2-8℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

储存缓冲液

10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3

防腐剂

0.02% Sodium azide

生化机理

Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development. Post-translational: Autophosphorylated. Phosphorylated by CDC2-CCNB1 complexes on undefined serine and threonine residues. The phosphorylation by CDC2-CCNB1 complexes may inhibit the catalytic activity.

免疫原

Recombinant protein of human PKMYT1 (AA 1-499).

宿主种属

小鼠(Mouse)

种属反应性

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

特异性

PKMYT1

阳性对照

WB: HepG2, HeLa, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF7 lysates. IF/ICC: COS7 cells. Flow Cytometry: HeLa, Jurkat cells.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Mouse IgG2a

克隆类型

单克隆抗体

纯化方法

Protein A/G purified

克隆号

OTI2B4

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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