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Product details

名称

Proteasome 20S beta 7/PSMB7 Mouse mAb

分子类型

抗体

别名

Proteasome 20S beta 7/PSMB7抗体 | Proteasome 20S beta 7/PSMB7单克隆抗体 | 蛋白酶体PSMβ7抗体

英文别名

物理外观

Liquid

货号

Ab123389-10μl

包装规格

10μl

级别

已验证

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

4°C 运输。收货后建议分装。储存于 -20°C 或 -80°C。避免冷冻/解冻循环。

储存缓冲液

10mM PBS, 50% Glycerol, 1% BSA, 0.02% sodium azide. pH 7.3.

防腐剂

0.02% Sodium azide

生化机理

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.

免疫原

Recombinant protein of human Proteasome 20S beta 7/PSMB7 (AA 58-277).

宿主种属

小鼠(Mouse)

种属反应性

人(Human), 大鼠(Rat), 小鼠(Mouse), 狗(Dog), 猴(Monkey) | 人(Human),大鼠(Rat),小鼠(Mouse),狗(Dog),猴(Monkey)

特异性

Proteasome 20S beta 7/PSMB7

阳性对照

WB: Hep G2, HeLa, Jurkat, MCF7, A549 and NIH/3T3 cell lysates. IF/ICC: COS7 cells.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Mouse IgG1

克隆类型

单克隆抗体

纯化方法

Protein G purified

克隆号

OTI4G9

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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