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Product details

名称

PTPRE Mouse mAb

分子类型

抗体

别名

PTPRE抗体 | PTPRE单克隆抗体 | 蛋白酪氨酸磷酸酶受体E抗体

英文别名

物理外观

Liquid

货号

Ab123903-10μl

包装规格

10μl

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存4℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

储存缓冲液

10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3.

防腐剂

0.02% Sodium azide

生化机理

Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function. Isoform 2 acts as a negative regulator of insulin receptor (IR) signaling in skeletal muscle. Regulates insulin-induced tyrosine phosphorylation of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1), phosphorylation of protein kinase B and glycogen synthase kinase-3 and insulin induced stimulation of glucose uptake. Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+).

免疫原

Recombinant full length protein of human PTPRE produced in HEK293T cell.

宿主种属

小鼠(Mouse)

种属反应性

人(Human), 大鼠(Rat), 小鼠(Mouse), 猴(Monkey) | 人(Human),大鼠(Rat),小鼠(Mouse),猴(Monkey)

特异性

PTPRE

阳性对照

WB: HEK293T transfected with pCMV6-ENTRY PTPRE cDNA for 48 hrs; HepG2, COS7 lysates. IHC: Human kidney, liver, liver carcinoma, ovary adenocarcinoma, pancreas, prostate carcinoma tissues. IF/ICC: COS7 cells transiently transfected with pCMV6-ENTRY PTPRE.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Mouse IgG2a

克隆类型

单克隆抗体

纯化方法

Protein A purified

克隆号

OTI4B2

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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