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Product details
名称
Recombinant SLC22A1/OCT1 Antibody
分子类型
抗体
别名
溶质载体家族蛋白22成员A1抗体 | 溶质载体家族蛋白22成员A1重组兔单抗
英文别名
hOCT1 | OCT1 | Slc22a1 | hOCT1 antibody | OCT1 antibody | Slc22a1 antibody
物理外观
Liquid
货号
Ab127845-10μl
包装规格
10μl
级别
重组
浓度
见COA
储存温度
-20°C储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
4°C 短期储存(1-2 周)。-20°C下长期保存(24个月)。收货后建议分装。避免冷冻/解冻循环。
储存缓冲液
10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4
防腐剂
0.02% Sodium azide
生化机理
可转运各种结构和分子量的有机阳离子,包括模型化合物 1-甲基-4-苯基吡啶鎓(MPP)、四乙胺(TEA)、N-1-甲基烟酰胺(NMN)、4-(4-(二甲基氨基)苯乙烯基)-N-甲基吡啶鎓(ASP),内源性化合物胆碱、胍、组胺、肾上腺素、肾上腺素、去甲肾上腺素和多巴胺,以及药物奎宁和二甲双胍。有机阳离子的转运受到多种化合物的抑制,如四甲基铵(TMA)、可卡因、利多卡因、NMDA 受体拮抗剂、阿托品、哌唑嗪、西咪替丁、TEA 和 NMN、胍乙啶、西咪替丁、胆碱、普鲁卡因胺、奎宁、四丁基铵和四戊基铵。以电性和不依赖 pH 值的方式转运有机阳离子。以双向方式在质膜上转运有机阳离子。转运精胺和亚精胺。通过近端肾小管上皮细胞的基底侧膜转运普拉克索。胆碱转运由 MMTS 激活。受多种细胞内信号通路调节,包括蛋白激酶 A 激活的抑制,以及钙调蛋白复合物、钙调蛋白依赖性激酶 II 和 LCK 酪氨酸激酶的内源性激活。
免疫原
A synthetic peptide derived from human SLC22A1(AA 100-150)
宿主种属
兔(Rabbit)
种属反应性
人(Human)
特异性
SLC22A1
阳性对照
WB: Ramos, Jurkat, HeLa, HEK293 and Hep G2 cell lysates.
SDS-PAGE
150 kDa
偶联
Unconjugated
亚型
Rabbit IgG
克隆类型
重组抗体
轻链亚型
kappa
纯化方法
Protein A purified
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
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「No related articles yet」
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Research chemical 10μl

Research chemical 10μl; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10μl.

item number:Ab127845-10μl
Product model:10μl
level: 10μl
Lead Time:30days
sold 788 Items
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10μl

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