Src (phospho Y529) Antibody

抗体

磷酸化Src原癌基因抗体 | 磷酸化Src原癌基因多克隆抗体 | Src (phospho Y529)抗体 | Src (phospho Y529)多克隆抗体 | SRC磷酸化抗体 | SRC磷酸化多克隆抗体

Src (phospho Y529) | p-Src (phospho Y529) | Src(Phospho-Tyr529) | ASV | Avian sarcoma virus | c SRC | CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA | cSrc | EC 2.7.10.2 | Neuronal CSRC tyr

Liquid

Ab129131-10μl

10μl

已验证

1.0 mg/mL

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。

10mM PBS, 50% Glycerol, 0.5% BSA, 0.02% Sodium azide, pH7.2

0.02% sodium azide

Non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, plays an important role in osteoclastic bone resorption. Both the formation of a SRC-PTK2B complex, and SRC kinase activity are necessary for this function. Once it is recruited to the activated integrins, by PTK2B, it phosphorylates CBL which in turn induces the activation and recruitment of phosphatidylinositol 3-kinase to the cell membrane in a signaling pathway that is critical for osteoclast function. Promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase. Phosphorylates RUNX3 and COX2 on tyrosine residues, TNK2 on 'Tyr-284' and CBL on 'Tyr-731'. Enhances DDX58/RIG-I-elicited antiviral signaling.

A synthetic peptide derived from human Src (phospho Y529) (AA 487-536).

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse), 猴(Monkey) | 人(Human),大鼠(Rat),小鼠(Mouse),猴(Monkey)

Src (phospho Y529)

WB: A549, NIH/3T3 lysates. IHC: Human breast carcinoma tissue.

150kDa

Unconjugated

Rabbit IgG

多克隆抗体

Immunogen affinity purified

Whole IgG

Columbina picui,Marmota,Nesospiza acunhae,Phyllostomus discolor,Saguinus oedipus