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Product details

名称

TIMM8A/DDP Mouse mAb

分子类型

抗体

别名

线粒体内膜转位酶8A/耳聋/肌张力障碍肽抗体 | 线粒体内膜转位酶8A/耳聋/肌张力障碍肽单克隆抗体

英文别名

DDP 1 | DDP | DDP1 | Deafness dystonia protein 1 | Deafness/dystonia peptide | DFN 1 | DFN1 | MGC12262 | Mitochondrial import inner membrane translocase subunit Tim8 A | MTS | TIM 8A | TIM8A | TIMM 8A | Translocase of inner mitochondrial membrane 8 homolo

物理外观

Liquid

货号

Ab131315-10μl

包装规格

10μl

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

储存缓冲液

10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3.

防腐剂

0.02% Sodium azide

生化机理

Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.

免疫原

Recombinant full length protein of human TIMM8A produced in E.coli.

宿主种属

小鼠(Mouse)

种属反应性

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

特异性

TIMM8A

阳性对照

WB: HEK293T transfected with pCMV6-ENTRY TIMM8A cDNA for 48 hrs, 293T, HepG2 lysates. IHC: Human adenocarcinoma of colon, liver, adenocarcinoma of endometrium, carcinoma of prostate tissues.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Mouse IgG1

克隆类型

单克隆抗体

克隆号

OTI5C8

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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