TMP21 Antibody

抗体

跨膜转运蛋白21抗体 | TMP21抗体 | TMP21多克隆抗体

p23 | TMP21 | p24d1 | S31I125 | Tmp-21-I | S31III125 | P24(DELTA) | 21 kDa transmembrane-trafficking protein | p24delta | TMED10 | TMP21Tmp-21-I | transmembrane emp24 domain-containing protein 10 | transmembrane emp24-like trafficking protein 10 (yeast) |

Liquid

Ab131740-10μl

10μl

无载体

0.5 mg/mL

-20°C储存

超低温冰袋运输

运输温度为 4°C。储存温度为 -20ºC。

10mM PBS, 0.09% Sodium azide, pH 7.4

0.09% Sodium azide

Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act togther with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1 (By similarity). In COPI vesicle-mediated retrograde transport involved in the biogenesis of COPI vesicles and vesicle coat recruitment. On Golgi membranes, acts as primary receptor for ARF1-GDP which is involved in COPI-vesicle formation. Increases coatomer-dependent GTPase-activating activity of ARFGAP2. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2LR1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Involved in trafficking of amyloid beta A4 protein and soluble APP-beta release (independent of modulation of gamma-secretase activity). As part of the presenilin-dependent gamma-secretase complex regulates gamma-cleavages of the amyloid beta A4 protein to yield amyloid-beta 40 (Abeta40). Involved in organization of the Golgi apparatus.

A synthetic peptide derived from human TMED10 (AA 156-185)

兔(Rabbit)

人(Human), 兔(Rabbit), 大鼠(Rat), 小鼠(Mouse), 牛(Cow) | 人(Human),兔(Rabbit),大鼠(Rat),小鼠(Mouse),牛(Cow)

TMP21

WB: HeLa, HEK293, Jurkat, Raji and NIH/3T3 cell lysates.

150 kDa

Unconjugated

Rabbit IgG

多克隆抗体

Protein A purified + Peptide affinity purified

Whole IgG