Recombinant TP53INP1 Antibody

抗体

p53诱导核蛋白1抗体 | p53诱导核蛋白1单克隆抗体 | p53诱导核蛋白1重组单克隆抗体 | TP53INP1抗体 | TP53INP1单克隆抗体 | TP53INP1重组单克隆抗体 | p53DINP1抗体 | p53DINP1单克隆抗体 | p53DINP1重组单克隆抗体

FLJ22139 antibody | p53 damage inducible nuclear protein 1 antibody | p53 dependent damage inducible nuclear protein 1 antibody | p53 inducible nuclear protein 1 antibody | p53 inducible p53DINP1 antibody | p53-dependent damage-inducible nuclear protein 1

Liquid

Ab132038-10μl

10μl

重组

见COA

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4

0.02% Sodium azide

Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.

A synthetic peptide derived from human p53 DINP1 (AA 100-168)

兔(Rabbit)

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

TP53INP1

WB: Mouse lung, Rat lung, Hep G2 and A549 lysates

150 kDa

Unconjugated

Rabbit IgG

重组抗体

kappa

Protein A purified

Whole IgG