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Product details

名称

Recombinant TRAF2 Antibody

分子类型

抗体

别名

TRAF2抗体 | 肿瘤坏死因子受体相关因子2抗体

英文别名

物理外观

Liquid

货号

Ab132148-10μl

包装规格

10μl

级别

重组

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

4°C 短期储存（1-2 周）。-20°C下长期保存（24个月）。收货后建议分装。避免冷冻/解冻循环。

储存缓冲液

10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH7.4

防腐剂

0.02% Sodium azide

生化机理

调节 NF-kappa-B 和 JNK 的活化，在调节细胞存活和凋亡中发挥核心作用。需要 IgM 到 IgG 的正常抗体同型转换。具有 E3 泛素蛋白连接酶活性，可促进目标蛋白（如 BIRC3、RIPK1 和 TICAM1）与 "Lys-63 "连接的泛素化。是多个 E3 泛素蛋白连接酶复合物的重要组成成分，它通过使目标蛋白与其他 E3 泛素连接酶接触，促进目标蛋白的泛素化。通过抑制 BIRC2 和 BIRC3 蛋白的自泛素化和随后的降解来调节它们的水平；这并不依赖于 TRAF2 的 RING 型锌指结构域。

免疫原

A synthetic peptide derived from human TRAF2 (AA 1-28)

宿主种属

兔(Rabbit)

种属反应性

人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)

特异性

TRAF2

阳性对照

WB: HeLa, Jurkat, Hep G2, MCF7, SH-SY5Y, THP-1, NIH/3T3 and C6 cell lysates. IF/ICC: HeLa cells.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Rabbit IgG

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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