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Product details

名称

Recombinant Transferrin Receptor Antibody

分子类型

抗体

别名

英文别名

T9 | TR | TFR | p90 | CD71 | TFR1 | TRFR | IMD46 | CD71 antigen | CD71TRFR | TfR (Transferrin R) | TfR (TransferrinR) | TFRC | transferrin receptor (p90, CD71) | transferrin receptor protein 1 | CD 71 antibody | CD71 antibody | CD71 antigen antibody | IMD

物理外观

Liquid

货号

Ab132242-10μl

包装规格

10μl

级别

重组

浓度

见COA

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。

储存缓冲液

50mM Tris-Glycine, 150mM NaCl, 40% Glycerol, 0.05% BSA, 0.01% Sodium azide, pH 7.4

防腐剂

0.01% Sodium azide

生化机理

细胞通过受体介导的内吞作用将配体占用的转铁蛋白受体吸收到特化的内体中。内体酸化导致铁释放。然后，转铁蛋白-受体复合物被回收到细胞表面，pH 值恢复中性，转铁蛋白与其受体的亲和力随之丧失。转铁蛋白受体是红细胞和神经系统发育所必需的（相似）。第二个配体--遗传性血色素沉着病蛋白 HFE 与转铁蛋白竞争一个重叠的 C 端结合位点。通过铁吸收积极调节 T 细胞和 B 细胞的增殖（PubMed:26642240）。 (微生物感染）充当新世界网状病毒的受体：Guanarito、Junin 和 Machupo 病毒的受体。

免疫原

Recombinant protein of human Transferrin Receptor

宿主种属

兔(Rabbit)

种属反应性

人(Human), 小鼠(Mouse) | 人(Human),小鼠(Mouse)

特异性

Transferrin Receptor

阳性对照

WB: K562, HeLa, MCF7, LNCaP and MDA-MB-231 cell lysates. IF/ICC: HeLa cells.

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Rabbit IgG

克隆类型

重组抗体

轻链亚型

kappa

纯化方法

Protein A purified

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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