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Product details
名称
TRIM33 Mouse mAb
分子类型
抗体
别名
TRIM33抗体
英文别名
ECTO | PTC7 | RFG7 | TF1G | TIF1G | TIFGAMMA | TIF1GAMMA | 8030451N04Rik antibody | AI413936 antibody | cb1085 antibody | DKFZp586K1123 antibody | E3 ubiquitin-protein ligase TRIM33 antibody | EC 6.3.2.- antibody | Ectodermin antibody | Ectodermin homolog
物理外观
Liquid
货号
Ab132507-10μl
包装规格
10μl
级别
已验证
浓度
0.5 mg/mL
储存温度
-20°C储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
4°C 短期储存(1-2 周)。-20°C下长期保存(12个月)。收货后建议分装。避免冷冻/解冻循环。
储存缓冲液
25322-68-3
防腐剂
0.02% Sodium azide
生化机理
作为一种 E3 泛素蛋白连接酶。通过泛素蛋白酶体途径促进 SMAD4 泛素化、核排斥和降解。根据 PubMed:16751102 的研究,它不会促进内源性 SMAD4 水平的降低。可能充当转录抑制因子。抑制对 TGF-beta/BMP 信号级联的转录反应。在细胞增殖控制中发挥作用。它与 SMAD2 和 SMAD3 的结合可刺激造血干细胞/祖细胞的红细胞分化(相似)。单泛素化 SMAD4 并作为 SMAD4 依赖性 TGF-beta/BMP 信号级联的抑制剂(SMAD4 的单泛素化阻碍了其与活化的 SMAD2/3 形成稳定复合物的能力,导致 TGF-beta/BMP 信号级联受到抑制)。
免疫原
Recombinant protein of human TIF1 gamma / TRIM33
宿主种属
小鼠(Mouse)
种属反应性
人(Human)
特异性
TRIM33
阳性对照
WB: MCF7 and HeLa lysates.
SDS-PAGE
150 kDa
偶联
Unconjugated
亚型
Mouse IgG2a
克隆类型
单克隆抗体
纯化方法
Immunogen affinity purified
克隆号
3H7C8B9
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
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「No technical documents」
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Research chemical 10μl; 0. 5 mg

Research chemical 10μl; 0. 5 mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10μl; 0. 5 mg.

item number:Ab132507-10μl
Product model:10μl
level: 10μl; 0. 5 mg
Lead Time:30days
sold 572 Items
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10μl

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