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Product details
名称
Recombinant Ubiquitin Antibody
分子类型
抗体
别名
泛素蛋白抗体 | 泛素蛋白单克隆抗体 | 泛素蛋白重组单克隆抗体 | Ubiquitin抗体 | Ubiquitin单克隆抗体 | Ubiquitin重组单克隆抗体 | UBB抗体 | UBB单克隆抗体 | UBB重组单克隆抗体
英文别名
HEL-S-50 | UBB | Ubiquitin/Ubiquitin+1 | Epididymis secretory protein Li 50 antibody | FLJ25987 antibody | HEL S 50 antibody | MGC8385 antibody | Polyubiquitin B antibody | RPS 27A antibody | RPS27A antibody | UBA 52 antibody | UBA 80 antibody | UBA52 ant
物理外观
Liquid
货号
Ab133323-10μl
包装规格
10μl
级别
重组
浓度
见COA
储存温度
-20°C储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
短期储存2-8℃(1-2周);长期储存-20℃(24个月);收货后建议分装,避免反复冻融。
储存缓冲液
10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4
防腐剂
0.02% Sodium azide
生化机理
泛素可与另一种蛋白质共价结合或游离(非锚定)存在。共价结合时,泛素通过异肽键与目标蛋白质结合,可以是单体(单泛素),也可以是通过泛素的不同 Lys 残基连接的聚合物(多泛素链),还可以是通过泛素的启动子 Met 连接的线性聚合物(线性多泛素链)。多泛素链连接到目标蛋白质后,会根据连接的泛素的 Lys 残基不同而具有不同的功能:连接 Lys-6 的泛素可能参与 DNA 修复;连接 Lys-11 的泛素参与 ERAD(内质网相关降解)和细胞周期调节;连接 Lys-29 的泛素参与溶酶体降解;连接 Lys-33 的泛素参与激酶修饰;连接的 Lys-48 参与蛋白酶体的蛋白质降解;连接的 Lys-63 参与内吞、DNA 损伤反应以及导致激活转录因子 NF-kappa-B 的信号转导过程。通过启动子 Met 的附着形成的线性聚合物链会导致细胞信号传导。泛素通常与目标蛋白质的赖氨酸残基结合,但在极少数情况下,也会与 Cys 或 Ser 残基结合。当多泛素是游离的(非锚定多泛素)时,它也有独特的作用,如激活蛋白激酶和传递信号。
免疫原
A synthetic peptide derived from human Ubiquitin (AA 50-76)
宿主种属
兔(Rabbit)
种属反应性
人(Human), 大鼠(Rat), 小鼠(Mouse) | 人(Human),大鼠(Rat),小鼠(Mouse)
特异性
Ubiquitin
阳性对照
WB: Mouse brain, Rat brain, Hep G2, HeLa, Jurkat, MCF7, SH-SY5Y and HEK293 lysates. IHC: Human breast cancer tissue. IF/ICC: Jurkat cells.
SDS-PAGE
150 kDa
偶联
Unconjugated
亚型
Rabbit IgG
克隆类型
重组抗体
轻链亚型
kappa
纯化方法
Protein A purified
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
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「No related articles yet」
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Research chemical 10μl

Research chemical 10μl; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10μl.

item number:Ab133323-10μl
Product model:10μl
level: 10μl
Lead Time:30days
sold 805 Items
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Specifications:

10μl

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