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Product details

名称

c-Fos Mouse mAb

分子类型

抗体

别名

英文别名

货号

Ab156213-10μl

包装规格

10μl

级别

无载体

浓度

≥95%(SDS-PAGE)

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

4°C 短期储存（1-2 周）。在 -20°C 或 -80°C 下保存。避免冷冻/解冻循环。

储存缓冲液

PBS, pH 7.2

生化机理

核磷蛋白，与 JUN/AP-1 转录因子形成紧密但非共价连接的复合物。在异源二聚体中，FOS 和 JUN/AP-1 的基本区似乎各自与对称的 DNA 半位点相互作用。在 TGF-beta 激活时，在 AP1/SMAD 结合位点形成多聚 SMAD3/SMAD4/JUN/FOS 复合物，以调节 TGF-beta 介导的信号传导。在调节细胞发育以形成和维持骨骼方面具有关键作用。它被认为在信号转导、细胞增殖和分化中发挥重要作用。在生长细胞中，可能通过激活 CDS1 和 PI4K2A 激活磷脂合成。这种活性需要 Tyr-去磷酸化以及与内质网的结合。

免疫原

Recombinant full length protein corresponding to human FOS

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

c-Fos

阳性对照

WB: U-2 OS whole cell lysate, HeLa and HeLa cells starved overnight and then stimulated with 20% FBS for 2 hours whole cell lysates

SDS-PAGE

150.0 KDa

偶联

Unconjugated

亚型

Mouse IgG1

克隆类型

单克隆抗体

轻链亚型

kappa

纯化方法

Protein A purified

克隆号

EF01/4H2

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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