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Product details

名称

Bax Mouse mAb

分子类型

抗体

别名

细胞凋亡调控因子 | BCL2相关X蛋白 | Bax抗体 | 小鼠抗人Bax抗体

英文别名

货号

Ab156543-10μl

包装规格

10μl

级别

无载体

浓度

≥95%(SDS-PAGE)

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融.

储存缓冲液

PBS, pH 7.4

生化机理

Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

免疫原

Recombinant protein corresponding to human Bax

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

Human Bax

阳性对照

Flow Cytometry: HeLa cells

SDS-PAGE

150.0 KDa

偶联

Unconjugated

亚型

Mouse IgG1

克隆类型

单克隆抗体

轻链亚型

kappa

纯化方法

Protein A purified

克隆号

CD01/2B7

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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