LC3B Mouse mAb

抗体

微管相关蛋白 1 轻链 3 beta | LC3B 抗体 | LC3B/MAP1LC3B 抗体 | MAP1LC3B 抗体 | MAP LC3beta 抗体

ATG8F antibody | Autophagy-related protein LC3 B antibody | Autophagy-related ubiquitin-like modifier LC3 B antibody | LC3B antibody | LC3II antibody | MAP1 light chain 3 like protein 2 antibody | MAP1 light chain 3-like protein 2 antibody | MAP1A/1BLC3 a

Ab156564-10μl

10μl

无载体

≥95%(SDS-PAGE)

-20°C储存,避免反复冻融

超低温冰袋运输

短期储存2-8℃ (1-2周); 长期储存-20℃ (24个月); 收货后建议分装，避免反复冻融.

PBS, pH 7.2

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover. Upon nutrient stress, directly recruits cofactor JMY to the phagophore membrane surfaces and promotes JMY's actin nucleation activity and autophagosome biogenesis during autophagy.

Synthetic peptide

小鼠(Mouse)

人(Human)

Human LC3B

Flow Cytometry: HeLa cells

150.0 KDa

Unconjugated

Mouse IgG2b

单克隆抗体

kappa

Protein A purified

LM01/4F7

Whole IgG