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Product details

名称

iNOS Mouse mAb

分子类型

抗体

别名

英文别名

货号

Ab169216-10μl

包装规格

10μl

级别

无动物源

浓度

≥95%(SDS-PAGE)

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

储存缓冲液

PBS, pH 7.2

生化机理

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of pro-inflammatory mediators such as IL6 and IL8.

免疫原

Recombinant protein corresponding to Human iNOS

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

Human iNOS

阳性对照

WB: Human serum Flow Cytometry: A549 cells IF/ICC: MCF-7 cells

SDS-PAGE

150.0 KDa

偶联

Unconjugated

亚型

Mouse IgG1

克隆类型

单克隆抗体

轻链亚型

kappa

纯化方法

Protein A purified

克隆号

AB01/2H7

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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