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名称
Rovelizumab (anti-CD11a&CD18), 整合素抗体;α L 亚基(抗原 CD11A (p180);淋巴细胞功能相关抗原 1;α 多肽);整合素抗体;β 2 亚基(补体成分 3 受体 3 和 4 亚基)
分子类型
抗体
别名
罗维珠单抗 | 罗维珠单抗(抗 CD11a&CD18)
英文别名
Lymphocyte function associated antigen, type 1, alpha subunit antibody | Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody | Antigen CD11A antibody | CD 11a antibody | CD11 antigen-like family member A antibody | C
物理外观
Liquid
货号
Ab175649-5mg
包装规格
5mg
级别
无动物源
浓度
≥95%(SDS-PAGE&SEC-HPLC)
储存温度
-80℃储存,避免反复冻融
运输条件
超低温冰袋运输
稳定性与储存
Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
储存缓冲液
Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂
No
生化机理
CD11a: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. CD18: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.
宿主种属
人(Human)
种属反应性
人(Human)
特异性
ITGAL; ITGB2
CAS编号和信息
339086-79-2
SDS-PAGE
145.98 kDa
偶联
Unconjugated
亚型
Human IgG4
克隆类型
重组抗体
轻链亚型
kappa
纯化方法
Protein A purified
作用类型
拮抗剂
作用机制
整合素抗体;α L 亚基(抗原 CD11A (p180);淋巴细胞功能相关抗原 1;α 多肽);整合素抗体;β 2 亚基(补体成分 3 受体 3 和 4 亚基)
Format
Whole IgG
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
Articles
「No related articles yet」
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Research chemical 5mg; ≥95%; HPLC

Research chemical 5mg; ≥95%; HPLC; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg; ≥95%; HPLC.

item number:Ab175649-5mg
Product model:5mg
level: 5mg; ≥95%; HPLC
Lead Time:30days
sold 847 Items
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5mg

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