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Product details

名称

CD40 Ligand/CD154 Mouse mAb

分子类型

抗体

别名

CD40配体 | CD154/CD40L单克隆抗体 | 小鼠抗人CD40 配体抗体

英文别名

货号

Ab178268-10μg

包装规格

10μg

级别

无载体

浓度

≥95%(SDS-PAGE)

储存温度

-20°C储存,避免反复冻融

运输条件

超低温冰袋运输

稳定性与储存

短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融.

储存缓冲液

PBS, pH 7.4

生化机理

Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4 (By similarity). Involved in immunoglobulin class switching (By similarity).

免疫原

Recombinant protein corresponding to human CD40LG

宿主种属

小鼠(Mouse)

种属反应性

人(Human)

特异性

Human CD40 Ligand

阳性对照

Flow Cytometry: PMA + Ionomycin-stimulated human PBMCs

SDS-PAGE

150 kDa

偶联

Unconjugated

亚型

Mouse IgG1

克隆类型

单克隆抗体

轻链亚型

kappa

纯化方法

Protein A purified

克隆号

AB06/3E2

Format

Whole IgG

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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